JICDRO is a UGC approved journal (Journal no. 63927)
REVIEW ARTICLE
Year : 2021  |  Volume : 13  |  Issue : 2  |  Page : 86-92

Oral cancer and genomics


1 Department of Oral Medicine and Radiology, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India
2 Graduate, BDS, Healing Touch Dental Clinic, Indrapuri, Bhopal, Madhya Pradesh, India

Correspondence Address:
Dr. Priyanka Deepak Deshmukh
Department of Oral Medicine and Radiology, People's College of Dental Sciences and Research Centre, Bhopal - 462 037, Madhya Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jicdro.jicdro_23_21

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Oral cancer is a leading cause of death, especially in developing countries. Head-and-neck squamous cell carcinoma is the sixth most common cancer worldwide. It accounts for 1.9% death annually due to delay in diagnosis and treatment strategies. Oral carcinogenesis is a multistep process. Recent advances in the understanding of the molecular control of these various pathways will facilitate more accurate diagnosis and assessment of prognosis and can pave the way for more novel approaches to treatment and prevention. This review highlights the major genes involved in oral carcinogenesis and emphasizes on the implementation of genomics, which can be the new paradigm for drug development and targeted therapeutics.


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