JICDRO is a UGC approved journal (Journal no. 63927)
Year : 2009  |  Volume : 1  |  Issue : 2  |  Page : 85-90

Efficacy and safety of dexketoprofen tablet in treatment of acute dental pain in Indian patients

Senior Lecturer, Department of Periodontics, Yogita Dental College, Khed, Ratnagiri, India

Correspondence Address:
Pankaj Chivte
Senior Lecturer, Department of Periodontics, Yogita Dental College, Khed, Ratnagiri
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Source of Support: None, Conflict of Interest: None

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Background: Dexketoprofen is the pharmacologically active enantiomer ofracemic Ketoprofen, and is indicated for the treatment of acute pain. Objective: To record the efficacy and safety of Dexketoprofen 25 mg Tablet in treatment of acute dental pain. Material and Methods: This was an observational, prescription event monitoring study in clinical setting. Indian male or female patients between 18-65 years of age who would be undergoing oral surgery consisting of extraction of the impacted or semi-impacted third molars or have acute dental pain and willing to comply with study were included. Patients were treated with Dexketoprofen Tablet 25 mg (Infen-25) every 8 hours preferably 30 min before meal. Efficacy was analyzed by decrease in pain on VAS (Visual Analogue Scale) and investigator's overall assessment of efficacy of therapy. Adverse events, if any, were noted. Results: Data of 3318 patients were analyzed. Mean baseline pain intensity on VAS decreased from 7.74 to 7.02, 5.48, 4 22, 3.31 and 2.52 at 10, 20, 30, 45 and 60 minutes, respectively, after drug administration. Investigators' overall assessment for efficacy was good to excellent in 96.5% patients, while investigators'Dexketoprofen was very well tolerated. Conclusion: Dexketoprofen Tablet provided rapid onset of action, with good tolerability and very high patient and investigator satisfaction.

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